:: Volume 29, Issue 2 (Summer 2011) ::
J Dent Sch GYEAR__, 29(2): 89-101 Back to browse issues page
Role of stem cell and new regenerative therapies in endodontics
Hengame Ashraf Dr., Maryam Kuzekanani Dr., Fateme Mohammadian Corresponding Author: Dr. *
Postgraduate Student Dept. of Endodontics , drmohammadianfatemeh@gmail.com
Abstract:   (7870 Views)

Background and Aim: Millions of teeth are saved each year by root canal therapy. Although current treatment modalities offer high levels of success for many condition, an ideal form of therapy might consist of regenerative approach in which a biologically based procedures designed to replace damaged structures, including dentin, root structure and pulp-dentin complex. The aim of this study was to collect information about the stem cell and their role in new regeneration therapies in endodontics.

Literature review: Data was collected by searching Pubmed and Cochrane data bases using key words such as stem cell, regenerative endodontics, pulp revascularization and tissue engineering. Selected reference text books were searched using the same search strategy. The search results was categorized according to methodological strength and selected only if qualified for our inclusion criteria. Although regenerative endodontic procedures are much more effective in regeneration of pulp-like tissue, ideally the pulp-dentin complex, but despite these applications and considerable evolution of certain medical procedures of tissue regeneration, there has not been significant translation of any these therapies into clinical endodontic practice.

Conclusion: More studies are required to overcome technical and clinical limitation of pulp and dentin tissue regeneration to not only result in pulp-dentin tissue regeneration, but also to form permanent teeth from stem cells.

Keywords: Stem cell, Endodontics, regeneration, pulp revascularization, Tissue engineering
Full-Text [DOCX 17 kb]   (1602 Downloads)    
Type of Study: Reviewed Article | Subject: Special
Received: 2011/06/7


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Volume 29, Issue 2 (Summer 2011) Back to browse issues page