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:: Volume 21, Issue 1 (Spring 2003) ::
J Dent Sch GYEAR__, 21(1): 1-7 Back to browse issues page
Diagnostic value of Nucleolar Organizer Regions (NORs) in salivary gland tumors
Behnam Eslami Corresponding Author: Dr. * , Estepan Alexanian Dr., Monir Moradzadeh Khiavi Dr., Mahmood Shahrokhi Dr.
Assistant Prof.
Abstract:   (7543 Views)

background & Aim: Several diagnostic methods are being employed to detect bening and malignant lesions. One of which is silver nitrate staining for nuclcolar organizer regions (NORs). Researches have shown such regions as being useful in comparison of the tumors for determination of changes. This study was designed to evaluate NROs as determinant for malignancy in sallivary gland lumors.

Methods & Materials: A silver colloid technique was applied on paraffin sections of 12 cases of pleomorphic adenoma, 12 cases of Mucoepidermoid carcinoma and 12 Adenoid cystic carcinoma. A group of 12 specimens were selected with normal salivary gland tissue.

Results: AgNORs were seen in 1.69±0.19 percent of the cases in normal tissue, 1.71±0.15 in pleomorphic adenoma, 2.18±0.94 in mucoepidermoid carcinoma and 2.61±0.45 in adenoid cystic carcinoma. Statistically significant differences were seen in AgNORs numbers between mucoepidermoid carcinoma and adenoid cysticcarcinoma with pleomorphic adenoma and normal tissue (P<1/0001) similar results were seen between the different histologic pattern in adenoid cystic carcinoma and pleomorphic adenoma (P<0.05).

Conclusion: The silver nitrate staining for nuclealar organizer (NORs) s a useful method for detection of malignant salivary gland tumors.

J Dent Sch 2003 21(1): 1 

Keywords: malignant, benign, salivary gland, AgNORs
     
Type of Study: Original Article | Subject: Special
Received: 2006/09/6
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Eslami B, Alexanian E, Moradzadeh Khiavi M, Shahrokhi M. Diagnostic value of Nucleolar Organizer Regions (NORs) in salivary gland tumors . J Dent Sch. 2003; 21 (1) :1-7
URL: http://jds.sbmu.ac.ir/article-1-732-en.html


Volume 21, Issue 1 (Spring 2003) Back to browse issues page
مجله دانشکده دندانپزشکی دانشگاه علوم پزشکی شهید بهشتی Shahid Beheshti University Dental Journal
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