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:: Volume 36, Issue 4 (Fall 2018) ::
J Dent Sch GYEAR__, 36(4): 118-121 Back to browse issues page
Pemphigus Disease: A geoepidemiologic preliminary study in Iran
Somayyeh Azimi1 , Jamileh Beigom Taheri2 , Zahra Namazi3, Sedigheh Bakhtiari4 , Nasrin Rafieian * 5
1- Honorary research fellow, International Research Collaborative – Oral Health and Equity, University of Western Australia, WA, Australia
2- Professor, Dept. of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3- PhD of Dental Materials, Tehran, Iran
4- Associate Professor, Dept. of Oral Medicine, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
5- Dietary Supplements and Probiotic Research Center, Alborz University of Medical Sciences, Karaj, Iran.
Abstract:   (975 Views)
Objectives Pemphigus is an autoimmune, life-threatening, blistering disease. Knowledge about the epidemiology of this disease however, is still limited. The aim of this study was to investigate the frequency and geographic distribution of pemphigus patients in Iran.
Methods Medical records of patients with definitive diagnosis of pemphigus disease during a seven-year period from March 2006 to March 2013 were retrospectively reviewed. All individuals were classified based on geographical aspects.
Results A total of 110 patients (59 females and 51 males) with an average age of 46.5 ± 13.6 for the females and 45.8± 12.5 for the males were evaluated. Male patients were slightly younger than female patients, but the difference was not statistically significant. Also, there was no significant association between age and the year of frequency. The most frequent type of pemphigus was the vulgaris type (93.6%). On the base of climate, the highest frequency was seen in the Moderate to severe internal (very hot) desert area and the humid and temperate climates (Caspian). There was no significant difference between the mean ages of pemphigus patients in the four geographic regions, (P value=0.421). Based on altitude in each climatic region, less than 10% of patients were from high altitude areas.
Conclusion Environmental factors are important in frequency of autoimmune disease including pemphigus.  We concluded that the frequency of pemphigus disease might be different in different climates and altitude. Further research towards the improvement of data on the geographical study could open up a field to identify the patterns of pemphigus disease
Keywords: Autoimmune disease, Pemphigus, Climate, Geography
Full-Text [PDF 527 kb]   (97 Downloads)    
Type of Study: Original Article | Subject: Special
Received: 2019/02/24 | Accepted: 2019/02/24 | Published: 2019/02/24
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Azimi S, Taheri J B, Namazi Z, Bakhtiari S, Rafieian N. Pemphigus Disease: A geoepidemiologic preliminary study in Iran . J Dent Sch. 2018; 36 (4) :118-121
URL: http://jds.sbmu.ac.ir/article-1-1710-en.html


Volume 36, Issue 4 (Fall 2018) Back to browse issues page
مجله دانشکده دندانپزشکی دانشگاه علوم پزشکی شهید بهشتی Shahid Beheshti University Dental Journal
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