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:: Volume 28, Number 4 (Winter 2011) ::
J Dent Sch GYEAR__, 28(4): 232-237 Back to browse issues page
In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Menta longifolia against three cariogenic bacteria
Dr. Hamid Kermanshah, Dr. Sedighe Sadat Hashemi Kamangar, Corresponding Author: Dr. Sakine Arami *, Dr. Akbar Mirsalehian, Mohammad Kamalinejad, Dr. Mehrdad Karimi, Dr. Fereshte Jebel Ameli
Assistant Professor
Abstract:   (8707 Views)

Background and Aim: The microbial cause of dental caries has been proved among its multifactorial etiologies. The prevention and control of dental caries is very critical because of high prevalence and cost especially in high risk patient such as xerostomia. Based on the world attraction to traditional treatment and importance of drug extraction of natural material and plants, in this in vitro study effect of hydroalcoholic extract of Salvia officinalis and Menta longifolia which were very useful in traditional treatment of mouth and teeth disease has been determined against cariogenic bacteria.

Materials & Methods: In this experimental study, hydroalcoholic extracts have been prepared from Salvia officinalis and Menta longifolia with maceration method. Their antibacterial activity against Streptococcus mutans, Lactobacillus rhamnosus and Actinomyces viscosus have been evaluated with broth macrodilution method. Results have been analyzed with Mann-Whitney test.

Results: Minimum inhibitory concentration for Salvia officinalis and Menta longifolia for streptococcus mutans were respectively 6.25 and 12.5 µg/ml, for Lactobacillus rhamnosus 1.56 and 3.12 µg/ml and for Actinomyces viscosus 12.5 and 100 µg/ml.

Conclusion: Both extracts had growth inhibitory effect on all three bacteria. Saliva officinalis had greater effect on inhibition of growth of all three bacteria (p<0.05). Both extracts had bactericidal effect in the range of studied concentrations.

J Dent Sch 2011 28(4): 232-237

Keywords: Cariogenic bacteria, Plant extract, Antibacterial activity, Salvia officinalis, Menta longifolia, Streptococcus mutans, Lactobacillus rhamnosus, Actinomyces viscosus
Full-Text [PDF 236 kb]   (3259 Downloads)    
Type of Study: Original Article | Subject: Special
Received: 2010/12/20
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Kermanshah H, Hashemi Kamangar S S, Arami S, Mirsalehian A, Kamalinejad M, Karimi M et al . In vitro evaluation of antibacterial activity of hydroalcoholic extract of Salvia officinalis and Menta longifolia against three cariogenic bacteria. J Dent Sch. 2011; 28 (4) :232-237
URL: http://jds.sbmu.ac.ir/article-1-850-en.html
Volume 28, Number 4 (Winter 2011) Back to browse issues page
مجله دانشکده دندانپزشکی دانشگاه علوم پزشکی شهید بهشتی Shahid Beheshti University Dental Journal
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