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:: Volume 36, Issue 1 (winter 2018) ::
J Dent Sch GYEAR__, 36(1): 23-26 Back to browse issues page
Silver staining efficiency in differential diagnosis of adenoid cystic carcinoma (ACC) from polymorpheus low-grade adenocarcinoma (PLGA)
Mahbube Valipour Tahamtan1, Shahrzad Shahbeik2, Alireza Abdollahi3, Gita Rezvani *4
1- Undergraduate Student, Dental School, Shahed University, Tehran, Iran.
2- Postgraduate Student, Dental School, Shahed University, Tehran, Iran.
3- Dept. of Pathology, Imam Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
4- Dept of Oral & maxillofacial Pathology, Faculty of Dentistry, Shahed University, Italy street, Vesal and Qods interval, Keshavarz Boulevard, Tehran, Iran , gitarez@yahoo.com
Abstract:   (904 Views)
Objectives The aim of this study is find a practical and easy way to histologically differentiate between two malignant
tumors namely Adenoid Cystic Carcinoma (ACC) and Polymorphous Low-grade Adeno Carcinoma (PLGA) silver nitrate
staining.

Methods In this cross-sectional study, 30 parrafin-embedded blocks of ACC and nine paraffin-embedded blocks of PLGA
with the most acceptable standards were selected and stained with silver nitrate. Then the number and quality (size
and pattern) of the stained spots in five random microscopic fields at 100× magnification (at least 100 cells) were
evaluated. T-test was used to compare the number of dots between the two tumors while the quality of dots was
compared with the Mann-Whitney U test.

Results The mean silver stainable nucleolus organizer region (AgNOR) count was 3/45 for ACC and 2/45 for PLGA.
Significant differences were observed in the number of dots between ACC and PLGA (p=0.004), but there was no
statistically significant difference between the two tumors in terms of quality of dots.

Conclusion AgNOR count can be useful as an available method in confirm the diagnosis of ACC and differentiate it from
PLGA.
Keywords: Carcinoma Adenoid Cystic, Adeno Carcinoma, Silver Nitrate, Cell Proliferation
Full-Text [PDF 606 kb]   (226 Downloads)    
Type of Study: Original Article | Subject: Special
Accepted: 2018/03/11 | Published: 2018/07/16
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Valipour Tahamtan M, Shahbeik S, Abdollahi A, Rezvani G. Silver staining efficiency in differential diagnosis of adenoid cystic carcinoma (ACC) from polymorpheus low-grade adenocarcinoma (PLGA). J Dent Sch. 2018; 36 (1) :23-26
URL: http://jds.sbmu.ac.ir/article-1-1660-en.html


Volume 36, Issue 1 (winter 2018) Back to browse issues page
مجله دانشکده دندانپزشکی دانشگاه علوم پزشکی شهید بهشتی Shahid Beheshti University Dental Journal
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