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:: Volume 32, Issue 4 (Fall 2014) ::
J Dent Sch GYEAR__, 32(4): 240-244 Back to browse issues page
Tongue squamous cell carcinoma in a patient with systemic sclerosis: A case report
Fatemeh Bagheri , Hamed Mortazavi , Maryam Baharvand *
Associate Professor , marbahar@gmail.com
Abstract:   (2499 Views)
Objective: Systemic sclerosis (SS) is a chronic autoimmune disease of connective tissue, which involves skin and internal organs, and results in collagen deposition and fibroblasts activation. Studies have reported a higher risk of malignancy in patients with progressive systemic sclerosis (PSS).The aim of this study is to report a case of tongue squamous cell carcinoma (SCC) in a patient with PSS. Case: A 46-year-old woman with SS presented to the Department of Oral Medicine of Shahid Beheshti University of Medical Sciences Dental School with chief complaint of an ulcer on her tongue. During intraoral examination, an asymptomatic ulcer measuring 2.0×1.5 cm was discovered on the right lateral border of the tongue. Incisional biopsy under local anesthesia was performed and histopathological report confirmed presence of squamous cell carcinoma. After further evaluation, surgery was performed, followed by three sessions of brachytherapy and six sessions of chemotherapy. After 26 months of follow-up, there was no evidence of recurrence. Conclusion: Periodic screening examinations are necessary to discover possible malignancies in primary stages in patients with SS.
Keywords: Squamous Cell Carcinoma, Systemic sclerosis, Tongue
Full-Text [PDF 239 kb]   (474 Downloads)    
Type of Study: Case Report | Subject: Special
Received: 2015/01/13 | Accepted: 2015/01/13 | Published: 2015/01/13
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Bagheri F, Mortazavi H, Baharvand M. Tongue squamous cell carcinoma in a patient with systemic sclerosis: A case report. J Dent Sch. 2014; 32 (4) :240-244
URL: http://jds.sbmu.ac.ir/article-1-1348-en.html

Volume 32, Issue 4 (Fall 2014) Back to browse issues page
مجله دانشکده دندانپزشکی دانشگاه علوم پزشکی شهید بهشتی Shahid Beheshti University Dental Journal
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